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Difficult Identification of Cuboid Syndrome

Tuesday, 07 November 2023 00:00

Cuboid syndrome has numerous alternate names, such as cuboid fault syndrome or lateral plantar neuritis. It manifests primarily as pain on the foot's outer edge, which stems from a misalignment of the cuboid bone. Located centrally within the foot, this bone connects seamlessly with other bones and is anchored by ligaments and tendons. A crucial joint in this context is the calcaneocuboid joint, vital for foot stability and motion. Problems arise when the bone displaces from its position, resulting in symptoms like pain, restricted motion, and challenges in weight-bearing. The diagnosis of cuboid syndrome often remains elusive as other issues can lead to lateral foot pain, such as gout, compression neuropathy, and tendinopathy. If cuboid syndrome is the culprit, treatment typically focuses on bone manipulation, with persistent cases demanding further interventions. If you have lateral foot pain, it is suggested that you make an appointment with a podiatrist for an examination, diagnosis, and treatment for its cause.

Cuboid syndrome, also known as cuboid subluxation, occurs when the joints and ligaments near the cuboid bone in the foot become torn. If you have cuboid syndrome, consult with Dr. Gary Cesar from Michigan Foot and Ankle Center. Our doctor will assess your condition and provide you with quality foot and ankle treatment.

Cuboid syndrome is a common cause of lateral foot pain, which is pain on the outside of the foot. The condition may happen suddenly due to an ankle sprain, or it may develop slowly overtime from repetitive tension through the bone and surrounding structures.


The most common causes of cuboid syndrome include:

  • Injury – The most common cause of this ailment is an ankle sprain.
  • Repetitive Strain – Tension placed through the peroneus longus muscle from repetitive activities such as jumping and running may cause excessive traction on the bone causing it to sublux.
  • Altered Foot Biomechanics – Most people suffering from cuboid subluxation have flat feet.


A common symptom of cuboid syndrome is pain along the outside of the foot which can be felt in the ankle and toes. This pain may create walking difficulties and may cause those with the condition to walk with a limp.


Diagnosis of cuboid syndrome is often difficult, and it is often misdiagnosed. X-rays, MRIs and CT scans often fail to properly show the cuboid subluxation. Although there isn’t a specific test used to diagnose cuboid syndrome, your podiatrist will usually check if pain is felt while pressing firmly on the cuboid bone of your foot.


Just as the range of causes varies widely, so do treatments. Some more common treatments are ice therapy, rest, exercise, taping, and orthotics.

If you have any questions, please feel free to contact our offices located in Lansing and Mt. Pleasant, MI . We offer the newest diagnostic and treatment technologies for all your foot care needs.


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